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Proteintech
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Immunogen sequence: SKASQQKIL SLTETIECLQ TNIDHLQSQV EELKSSGQGR RSPGKCDQEK PAPSFACLKE LYDLRQHFVY DHVFAEKITS LQGQPSPDEE ENEHLKKTVT MLQAQLSLER QKRVTMEEEY GLVLKENSEL EQQLGATGAY RARALELEAE VAEMRQMLQS EHPFVNGVEK LVPDSLYVPF KEPSQSLLEE MFLTVPESHR KPLKRSSSET ILSSLAGSDI VKGHEETCIR RAKAVKQRGI SLLHEVDTQY SALKVKYEEL LKKCQEEQDS LSHKAVQTSR AAAKDLTGVN AQSEPVASGW ELASVNPEPV SSPTTPPEYK ALFKEIFSCI KKTKQEIDEQ RTKYRSLSSH S (105-454 aa encoded by BC017503)
Using anti-Yo antibodies, three genes have been cloned (CDR 1-3). CDR2 suppresses the transcriptional activity and DNA binding of nuclear factor-kappa B by an unknown mechanism. The neuron specific expression of CDR2 is regulated by a post-transcriptional mechanism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cerebellar degeneration-related protein 2; cerebellar degeneration-related protein 2, 62kDa; Major Yo paraneoplastic antigen; Paraneoplastic cerebellar degeneration-associated antigen; Yo paraneoplastic antigen
Gene Aliases: AA617262; CDR2; CDR62; PCD17; Yo
UniProt ID: (Human) Q01850, (Mouse) P97817
Entrez Gene ID: (Human) 1039, (Mouse) 12585
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