Invitrogen

CDK1/CDK2 Monoclonal Antibody (AN21.2)

View all (4) CDK1/CDK2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

MA1-91380

Applications
Tested Dilution
Publications

Western Blot (WB)

2 µg/mL
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

AN21.2

Immunogen

Human cdk2.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1955514

Product Specific Information

Recommended positive controls: HeLa nuclear extract.

Target Information

Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: cdc2-related protein kinase; CDK1; cell cycle controller CDC2; Cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; Cell division protein kinase 1; Cell division protein kinase 2; Cyclin-dependent kinase 1; Cyclin-dependent kinase 2; p33 protein kinase; p34 protein kinase

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Gene Aliases: CDC2; CDC28A; CDK1; CDK2; CDKN1; CDKN2; p33(CDK2); P34CDC2

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UniProt ID: (Human) P06493, (Human) P24941

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Entrez Gene ID: (Human) 983, (Human) 1017

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Function(s)
protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity cyclin binding Hsp70 protein binding histone kinase activity kinase activity protein complex binding metal ion binding
Process(es)
G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle lens development in camera-type eye DNA replication DNA repair potassium ion transport DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest mitotic nuclear division centriole replication meiotic nuclear division Ras protein signal transduction positive regulation of cell proliferation response to toxic substance histone phosphorylation peptidyl-serine phosphorylation organ regeneration mitotic G1 DNA damage checkpoint positive regulation of DNA-dependent DNA replication initiation response to estradiol cellular response to insulin stimulus response to drug response to ethanol positive regulation of transcription, DNA-templated response to cadmium ion centrosome duplication cell division negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle response to cAMP response to electrical stimulus regulation of gene silencing cellular response to nitric oxide regulation of signal transduction by p53 class mediator regulation of transcription involved in G1/S transition of mitotic cell cycle activation of MAPK activity microtubule cytoskeleton organization protein complex assembly apoptotic process mitotic nuclear envelope disassembly mitotic G2 DNA damage checkpoint centrosome cycle pronuclear fusion cell aging positive regulation of gene expression regulation of Schwann cell differentiation response to organic cyclic compound response to amine response to activity cell migration peptidyl-threonine phosphorylation chromosome condensation epithelial cell differentiation anaphase-promoting complex-dependent catabolic process positive regulation of protein import into nucleus, translocation protein localization to kinetochore protein ubiquitination involved in ubiquitin-dependent protein catabolic process negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of DNA replication positive regulation of mitotic cell cycle regulation of embryonic development response to copper ion response to axon injury positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition ventricular cardiac muscle cell development positive regulation of cardiac muscle cell proliferation cellular response to hydrogen peroxide Golgi disassembly positive regulation of protein localization to nucleus
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