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          • Primary Antibodies ›
          • CDH8 Antibodies

          Invitrogen

          CDH8 Polyclonal Antibody

          View all (6) CDH8 antibodies

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          Cite CDH8 Polyclonal Antibody

          • Antibody Testing Data (4)
          CDH8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CDH8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 4

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          CDH8 Antibody (PA5-86480) in IHC (P)

          Immunohistochemical analysis of CDH8 in paraffin-embedded human brain tissue. Sample was incubated with polyclonal CDH8 antibody (Product # PA5-86480). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CDH8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CDH8 Antibody in Western Blot (WB)
          CDH8 Antibody in Western Blot (WB)
          CDH8 Antibody in Western Blot (WB)

          Product Details

          PA5-86480

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide, corresponding to amino acids 500-550 of Human Cadherin-8.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2803258

          Product Specific Information

          Purity is > 95% by SDS-PAGE.

          Target Information

          CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: CADH8; Cadherin; cadherin 8, type 2; Cadherin-8; Cadherin8

          View more View less

          Gene Aliases: AI851472; cad8; CDH8; Nbla04261

          View more View less

          UniProt ID: (Human) P55286, (Mouse) P97291

          View more View less

          Entrez Gene ID: (Human) 1006, (Mouse) 12564, (Rat) 84408

          View more View less

          Function(s)
          calcium ion binding metal ion binding
          Process(es)
          cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules response to cold adherens junction organization synaptic transmission, glutamatergic chemical synaptic transmission spermatogenesis single organismal cell-cell adhesion
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

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