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PA1-31120 detects CCKBR from human samples.
PA1-31120 has been successfully used in immunohistochemistry (paraffin tissue), Western blot applications.
The PA1-31120 immunogen is: Poly Lysin conjugated synthetic peptide: VHRWPSARVRQTWS, corresponding to amino acids 206-219 of Human CCKBR.
CCKBR is a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR has been reported in brain, colon, pancreas, stomach, thyroid, and various cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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