Proteintech

CC2D1B Polyclonal Antibody

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CC2D1B Antibody (20774-1-AP) in WB

Human placenta tissue were subjected to SDS PAGE followed by western blot with 20774-1-AP (CC2D1B antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

CC2D1B Antibody in Immunoprecipitation (IP)

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Product Details

20774-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CC2D1B Fusion Protein Ag14767 (468-767 aa encoded by BC007912)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is specific to CC2D1B, which has been confirmed by siRNA test.

Immunogen sequence: VAATLAAAE KLASAEDSAP ADKDEDEGEP PAQAPVAKKP ARPTVPSSQR LPEPRASSSK ESPSPSVREQ LALLEARKLQ YQRAALQAKR SQDLEQAKAY LRVAKWLEAQ IIQARSGRPV DLSKVPSPLT DEEGDFILIH HEDLRLSQKA EEVYAQLQKM LLEQQEKCLL FSKQFMHQGN VAETTRFEKL AQDRKKQLEI LQLAQAQGLD PPTHHFELKT FQTVRIFSEL NSTEMHLIIV RGMNLPAPPG VTPDDLDAFV RFEFHYPNSD QAQKSKTAVV KNTNSPEFDQ LFKLNINRNH R (468-767 aa encoded by BC007912)

Target Information

Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Cc2d1b Contributes to the Regulation of Developmental Myelination in the Central Nervous System.

Frontiers in molecular neuroscience

Acheta J,Hong J,Jeanette H,Brar S,Yalamanchili A,Feltri ML,Manzini MC,Belin S,Poitelon Y

Fri Dec 09 00:00:00 UTC 2022

YAP and TAZ Regulate Cc2d1b and Purβ in Schwann Cells.

Frontiers in molecular neuroscience

Sophie B,Jacob H,Jordan VJS,Yungki P,Laura FM,Yannick P

Thu Oct 01 00:00:00 UTC 2020

YAP and TAZ Regulate Cc2d1b and Purβ in Schwann Cells.

Frontiers in molecular neuroscience

Sophie B,Jacob H,Jordan VJS,Yungki P,Laura FM,Yannick P

Thu Oct 01 00:00:00 UTC 2020

The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling.

PLoS genetics

Drusenheimer N,Migdal B,Jäckel S,Tveriakhina L,Scheider K,Schulz K,Gröper J,Köhrer K,Klein T

Tue Dec 01 00:00:00 UTC 2015

The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling.

PLoS genetics

Drusenheimer N,Migdal B,Jäckel S,Tveriakhina L,Scheider K,Schulz K,Gröper J,Köhrer K,Klein T

Tue Dec 01 00:00:00 UTC 2015

The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling.

PLoS genetics

Drusenheimer N,Migdal B,Jäckel S,Tveriakhina L,Scheider K,Schulz K,Gröper J,Köhrer K,Klein T

Tue Dec 01 00:00:00 UTC 2015

The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling.

PLoS genetics

Drusenheimer N,Migdal B,Jäckel S,Tveriakhina L,Scheider K,Schulz K,Gröper J,Köhrer K,Klein T

Tue Dec 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: Coiled-coil and C2 domain-containing protein 1B; Five prime repressor element under dual repression-binding protein 2; FRE under dual repression-binding protein 2; freud-2

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Gene Aliases: A830039B04Rik; CC2D1B; Freud2; KIAA1836; LGD1; RGD1306630

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UniProt ID: (Human) Q5T0F9, (Rat) Q5FVK6, (Mouse) Q69Z95

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Entrez Gene ID: (Human) 200014, (Rat) 313478, (Mouse) 319965

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Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding protein binding

Process(es)

negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated transcription from RNA polymerase II promoter regulation of transcription, DNA-templated

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CC2D1B Polyclonal Antibody

CC2D1B Antibody (20774-1-AP) in WB

Product Details

20774-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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