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PA1-24713 detects CA150 from human samples. PA1-24713 is expected to cross react with mouse due to sequence homology.
PA1-24713 has been successfully used in Western blot procedures.
The PA1-24713 immunogen is a synthetic peptide corresponding to a portion of human transcription elongation regulator 1 (CA150) encoded within exon 1 (LocusLink ID 10915).
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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