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S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU) (PubMed:25063302). The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability. May bind to tRNA. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: likely ortholog of H. sapiens chromosome 9 open reading frame 156 (C9orf156); Nef (lentivirus myristoylated factor) associated protein 1; Nef associated protein 1; nef-associated protein 1; thioesterase NAP1; tRNA (adenine(37)-N6)-methyltransferase; tRNA methyltransferase O
Gene Aliases: AV014846; C9orf156; HSPC219; NAP1; TRMO
UniProt ID: (Mouse) Q562D6, (Rat) Q4V7E0, (Human) Q9BU70
Entrez Gene ID: (Mouse) 74753, (Rat) 298072, (Human) 51531
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