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Invitrogen
Brevican Polyclonal Antibody
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Product Details
PA1-31195
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic C terminal peptide for particulate guanylyl cyclase B. (unfortunately, the amino acid sequence is considered to be commercially sensitive). All peptides were amidated for conjugation.
Conjugate
Form
Liquid
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_1959516
Product Specific Information
PA1-31195 detects PGCB from human, rat samples.
PA1-31195 has been successfully used in Western blot applications.
The PA1-31195 immunogen is: Synthetic C terminal peptide for particulate guanylyl cyclase B. (unfortunately, the amino acid sequence is considered to be commercially sensitive). All peptides were amidated for conjugation.
Target Information
Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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