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A 1:1,000 dilution of PA5-77774 was sufficient for detection of Beclin2 on rat liver lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.|Predicted molecular weight at approximately 48.1kDa. Observed bands in the 50-55kDa range, varied by lysates.
Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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