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Invitrogen
Bcl-3 Polyclonal Antibody
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FIGURE: 1 / 1
Bcl-3 Antibody (PA5-28783) in WB, GS
mBio 2019 -
FIG 3 Macrophages were left uninfected or infected with HIV for 10 days. (A) Cells were harvested and lysed. (Left) Representative Western blots of TREM1 with antibodies against TREM1 and ACTB. (Right) Densitometric analysis of blots, n = 4. (B) Cells were transfected with RELA siRNA (si RELA ) or scrambled siRNA (siNS). (Left) Representative Western blots of RELA, TREM1, and ACTB. (Right) Densitometric ana... View More
Product Details
PA5-28783
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 1 and 45 of BCL3
Conjugate
Form
Liquid
Concentration
0.72 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2546259
Product Specific Information
PA5-28783 targets BCL3 in IF and WB applications and shows reactivity with Human samples.
The PA5-28783 immunogen is a synthetic peptide corresponding to a region within amino acids 1 and 45 of BCL3.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Target Information
B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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