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Invitrogen
BRD2 Polyclonal Antibody
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Product Details
PA1-26576
Product Specifications
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a portion of human Bromodomain Containing 2 (BRD 2) between the putative nuclear localization signal and the ET dom
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
Product Specific Information
PA1-26576 detects BRD2 from human samples. PA1-26576 is expected to cross react with mouse due to sequence homology.
PA1-26576 has been successfully used in Western blot procedures. The predicted molecular weight is 110 kDa. A suggested positive control for this product is HeLa cell extract.
The PA1-26576 immunogen is a synthetic peptide corresponding to a portion of human Bromodomain Containing 2 (BRD 2) between the putative nuclear localization signal and the ET domain.
Target Information
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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