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Invitrogen
BAZ2A Polyclonal Antibody
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Product Details
PA5-66636
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human TIP5
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2665089
Product Specific Information
Immunogen sequence: SLEVPLTASVT SPKASPVTSP AAAFPTASPA NKDVSSFLET TADVEEITGE GLTASGSGDV MRRRIATPEE VRLPLQHGWR REVRIKKGSH R
Highest antigen sequence identity to the following orthologs - mouse 71%, rat 63%.
Target Information
TIP 5 is the large subunit of the nucleolar remodeling complex NoRC. NoRC causes the repression of ribosomal gene transcription. It was demonstrated that histone deacetylation is involved in this repression and that TIP5 is associated with the histone deacetylase HDAC1 and mediates the deacetylation of histones in the vicinity of the rDNA promoter. The interaction of TIP5 and HDAC1, which is necessary for transcriptional repression, is established by the C-terminal PHD finger and bromodomain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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