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Invitrogen
Aurora A Polyclonal Antibody
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FIGURE: 1 / 1
Aurora A Antibody (PA1-28087) in WB
Western blot analysis of Aurora A using whole tissue lysate (60µg/lane) from rat mammary glands. Samples were probed with an Aurora A polyclonal antibody (Product # PA1-28087) at a dilution of 0.2µg/ml. Detection was performed using chemiluminescence with an exposure time of 6 minutes. The upper band is believed to be phosphorylated Aurora A.
Product Details
PA1-28087
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Immunogen was a synthetic peptide, which represented a C-terminal domain of mouse Aurora Kinase A (LocusLink ID 20878).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
PA1-28087 detects Aurora A from mouse and rat samples.
PA1-28087 has been successfully used in immunofluorescence, Western blot applications.
The PA1-28087 immunogen is: Immunogen was a synthetic peptide, which represented a C-terminal domain of mouse Aurora Kinase A (LocusLink ID 20878).
Target Information
AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association in vivo with centrosomes. Overexpression of AURKA is observed in many types of cancer. Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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