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FIGURE: 1 / 1
Immunogen sequence: ANRNWNSPVA NFIMESQRLE LIRLMETQEE DVVLLTAGEH NKACSLLGKL RLECADLLET RGVVLRDPTL FSFLWVVDFP LFLPKEENPR ELESAHHPFT APHPSDIHLL YTEPKKARSQ HYDLVLNGNE IGGGSIRIHN AELQRYILAT LLKEDVKMLS HLLQALDYGA PPHGGIALGL DRLICLVTGS PSIRDVIAFP KSFRGHDLMS NTPDSVPPEE LKPYHIRVSK PTDSKAERAH; Positive Samples: NCI-H460, MCF7, BT-474, Mouse liver; Cellular Location: Mitochondrion matrix
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
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