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PA1-27803 detects ANXA9 from human samples.
PA1-27803 may be successfully used in ELISA and Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27671 immunogen is a synthetic peptide corresponding to human Annexin A9.
The annexins include ANXA9 coded protein, which are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. Annexin A9 is a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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