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Invitrogen
Amylin Polyclonal Antibody
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Product Details
PA1-36038
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Amylin.
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage conditions
4°C
Shipping conditions
Wet ice
RRID
AB_2233547
Product Specific Information
Suggested positive controls for IHC include human and rat pancreas. Recommended dilutions are 1:800-1:1500 using PAP, or 1:300-1:500 using FITC with over-night incubation at 4°C.
Reconstitute with 50-100 µL of distilled water, and dilute further in 0.1M PBS with 1% BSA and 0.1% sodium azide. For long-term storage, aliquot and store at -20°C.
Target Information
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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