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Invitrogen
ALKBH3 Polyclonal Antibody
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ALKBH3 Antibody (PA5-49622) in IHC (P)
Immunohistochemical analysis of ALKBH3 in Formalin-fixed and paraffin-embedded human prostate carcinoma tissue. Samples were probed with a ALKBH3 Antibody (C-term) (Product # PA5-49622) followed by peroxidase-conjugation to the secondary antibody, and DAB staining.
Product Details
PA5-49622
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 242-269 amino acids from the C-terminal region of human ALKBH3.
Conjugate
Form
Liquid
Concentration
Lot-Specific
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2635076
Product Specific Information
Predicted to react with bovine based on sequence homology.
Target Information
Dioxygenase that repairs alkylated DNA containing 1- methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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