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PA1-24972 detects MSH gamma 3 from rat samples. PA1-24972 is expected to cross react with human (86% conserved), mouse (92% conserved), chimpanzee (94% conserved), canine (85% conserved), gorilla (86% conserved), orangutan (86% conserved), leech (90% cons
PA1-24972 has been successfully used in immunohistochemistry (frozen) procedures.
The PA1-24972 immunogen is a synthetic peptide corresponding to residues K Y V M G H F R W D R F G P R N S S S A G G S A Q of rat MSH gamma 3.
ATCH (adrenocorticotropic hormone) is a hormone which plays a major role in stimulating the adrenal cortex. It is formed through cleavage of the polypeptide precursor proopiomelanocortin (POMC), which also results in several other cleavage products including MSH, ACTH, and beta endorphin. ATCH is secreted from the anterior pituitary in response to the corticotropin-releasing hormone from the hypothalamus. It stimulates the secretion of glucocorticoids like cortisol, but has little control over the stimulation of mineralocorticoids like aldosterone, which is another major hormone of the adrenal cortex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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