PPM1G Proteins

Protein Information

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Synonyms

AI385652; fibroblast growth factor inducible 13; fibroblast growth factor-inducible protein 13; Fin13; PP2C, gamma; PP2CG; PP2CGAMMA; PP2C-gamma; Ppm1c; Ppm1g; PPP2CG; Protein phosphatase 1C; protein phosphatase 1G; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase 2, catalytic subunit, gamma isoform; protein phosphatase 2C gamma isoform; protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; protein phosphatase, Mg2+/Mn2+ dependent 1G; protein phosphatase, Mg2+/Mn2+ dependent, 1G