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          PIP5K1A Proteins

          PIP5K1A Human recombinant proteins are validated for use in the following applications: Blocking Assay and Kinase Assay. These proteins are expressed in E. coli and Insect cells. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed?... PIP5K1A Human recombinant proteins are validated for use in the following applications: Blocking Assay and Kinase Assay. These proteins are expressed in E. coli and Insect cells. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed?... PIP5K1A Human recombinant proteins are validated for use in the following applications: Blocking Assay and Kinase Assay. These proteins are expressed in E. coli and Insect cells. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... PIP5K1A Human recombinant proteins are validated for use in the following applications: Blocking Assay and Kinase Assay. These proteins are expressed in E. coli and Insect cells. Available Product Grades: RUO. Browse all 2 proteins. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

          Protein Information

          PIP5K1A lipid kinase or phosphatidylinositol-4-phosphate 5-kinase 1 alpha phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1 is required for Wnt3a-induced LRP6 phosphorylation at ser1490 in mammalian cells. Wnt3a stimulates the formation of phosphatidylinositol 4,5-bisphosphates through 'frizzled' and 'disheveled', the latter of which directly interacts with and activated PIP5KI. PIP5K1A-mediated PIP(2) production is crucial for HIV-1 entry and the early steps of infection in permissive lymphocytes. Overexpression of wild-type PI4P5K1A increases HIV-1 Env-mediated PIP(2) production and enhances viral replication in primary lymphocytes.

          Synonyms

          68 kDa type I phosphatidylinositol 4-phosphate 5-kinase; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase; 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha; phosphatidylinositol 4-phosphate 5-kinase type I alpha; Phosphatidylinositol 4-phosphate 5-kinase type I beta; Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; phosphatidylinositol-4-phosphate 5-kinase; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha; phosphatidylinositol-4-phosphate 5-kinase type I alpha; phosphatidylinositol-4-phosphate 5-kinase type-1 alpha; phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha; phosphatidylinositol-4-phosphate 5-kinase, type 1 beta; phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha; PI4P5K-I[a]; PI4P5KIbeta; PI51A; PIP5K1A; PIP5K1-alpha; Pip5k1b; PIP5KIalpha; Pipk5a; ptdIns(4)P-5-kinase 1 alpha

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Invitrogen
          Human PIP5K1A, GST Tag Recombinant Protein
          Invitrogen
          Human PIP5K1A, GST Tag Recombinant Protein
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          Human
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          Insect cells
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          Research Use Only
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          Cat # A33520

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