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Product Details
217-17RA-50UG
Product Specifications
Species
Mouse
Expression System
CHO cells
Amino acid sequence
ESGNAQDGDL EDADADDHSF WCHSQLEVDG SQHLLTCAFN DSDINTANLE FQICGALLRV KCLTLNKLQD IYFIKTSEFL LIGSSNICVK LGQKNLTCKN MAINTIVKAE APSDLKVVYR KEANDFLVTF NAPHLKKKYL KKVKHDVAYR PARGESNWTH VSLFHTRTTI PQRKLRPKAM YEIKVRSIPH NDYFKGFWSE WSPSSTFETP EPKNQGGWDG GPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK
Tag
Fc-tag
Molecular weight
51 kDa
Class
Recombinant
Type
Protein
Purity
= 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to bind immobilized Murine IL-7 in a functional ELISA.
Conjugate
Form
Lyophilized
Purification
SDS-PAGE, HPLC
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Interleukin-7 is a glycoprotein involved in the regulation of lymphopoiesis. The response of cells to IL-7 is dependent on the
presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. Recombinant Murine sIL-7 Receptor a Fc is a 51.0 kDa protein containing 452 amino
acid residues consisting of the extracellular domain of the mature sequence, as well as a 230 C-terminal Fc region linked by two
glycines.
Target Information
Interleukin 7 (IL-7) is a hematopoietic cytokine that is constitutively produced by stromal cells from the bone marrow and thymus. IL-7 signals through the IL-7R to promote the differentiation of hematopoietic stem cells to lymphoid precursor cells, which give rise to T cells, B cells, and natural killer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD127; H-IL-7; IL-7; IL-7 receptor alpha chain; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; ILN; Interleukin; interleukin 7 receptor alpha chain; Interleukin-7; Interleukin-7 receptor subunit alpha; Interleukin7; M-IL-7
Gene Aliases: A630026I06Rik; CD127; hlb368; Il-7; IL-7Ralpha; Il7; Il7r
UniProt ID: (Mouse) P10168, (Mouse) P16872
Entrez Gene ID: (Mouse) 16196, (Mouse) 16197
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