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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67069. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ10407; FLJ12556; FLJ34120; hNDC1; nuclear division cycle 1 homolog; Nucleoporin NDC1; RP4-654H19.1; Transmembrane protein 48
Gene Aliases: NDC1; NET3; TMEM48
UniProt ID: (Human) Q9BTX1
Entrez Gene ID: (Human) 55706
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