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Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-62647. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a tetraspanin protein that is thought to be involved in WNT signaling. Defects in this gene are a cause of Joubert syndrome-14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein; Transmembrane protein 237
Gene Aliases: ALS2CR4; JBTS14; TMEM237
UniProt ID: (Human) Q96Q45
Entrez Gene ID: (Human) 65062
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