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Invitrogen
Human SMYD5 (aa 117-215) Control Fragment Recombinant Protein
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Product Details
RP-103042
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
MYCSAECRLAATEQYHQVLCPGPSQDDPLHPLNKLQEAWRSIHYPPETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANEEEEIVHKLLGDKFKG
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61859. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Retinoic acid (RA) represents the oxidized form of vitamin A and, via interactions with retinoic acid receptors (RARs), plays a crucial role in development, cellular growth and differentiation. The gene encoding RAI15 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [histone H3]-lysine20 N-trimethyltransferase SMYD5; [histone H4]-lysine36 N-trimethyltransferase SMYD5; Protein NN8 4AG; Protein NN8-4AG; Protein-lysine N-trimethyltransferase SMYD5; retinoic acid induced 15; retinoic acid responsive; Retinoic acid-induced protein 15; SET and MYND domain-containing protein 5
Gene Aliases: NN8-4AG; RAI15; RRG1; SMYD5; ZMYND23
UniProt ID: (Human) Q6GMV2
Entrez Gene ID: (Human) 10322
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