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This peptide corresponds to 17 amino acids near the amino terminus of human SHQ1.
PEP-1491 can be used as a blocking peptide with polyclonal antibody PA5-34449.
SHQ1 is the human homolog of yeast Shq1p, a protein that acts as an accessory factor in the assembly of H/ACA ribonucleoproteins. SHQ1 has been shown to bind the major H/ACA core protein and the pseudouridine synthase NAP57, but precedes the assembly role of NAF1 and of the other H/ACA core proteins. SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ10539; gene associated with retinoid and interferon-induced mortality 1; Protein SHQ1 homolog; SHQ1 homolog
Gene Aliases: GRIM-1; SHQ1; Shq1p
UniProt ID: (Human) Q6PI26
Entrez Gene ID: (Human) 55164
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