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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82527. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PRKX is a serine/threonine kinase related to the catalytic subunit of the cAMP-dependent protein kinases. PRKX is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cAMP-dependent protein kinase catalytic subunit PRKX; PrKX; Protein kinase PKX1; protein kinase X; serine/threonine-protein kinase PRKX
Gene Aliases: PKX1; PRKX
UniProt ID: (Human) P51817
Entrez Gene ID: (Human) 5613
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