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Invitrogen
Human PPM1H (aa 93-153) Control Fragment Recombinant Protein
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Product Details
RP-102962
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
EDQASCEVLTVKKKAGAVTSTPNRNSSKRRSSLPNGEGLQLKENSESEGVSCHYWSLFDGH
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60656. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neurite extension-related protein phosphatase related to PP2C; Protein phosphatase 1H; protein phosphatase 1H (PP2C domain containing); protein phosphatase, Mg2+/Mn2+ dependent, 1H; ras homolog gene family, member C like 1
Gene Aliases: ARHCL1; KIAA1157; NERPP-2C; PPM1H; URCC2
UniProt ID: (Human) Q9ULR3
Entrez Gene ID: (Human) 57460
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