Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Human PLEKHJ1 (aa 78-147) Control Fragment Recombinant Protein
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
RP-98922
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
FIEDPERKYHFECSSEEQCQEWMEALRRASYEFMRRSLIFYRNEIRKVTGKDPLEQFGISEEARFQLSGL
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61857. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The PLEKHJ1 (Pleckstrin Homology Domain Containing, Family J Member 1) gene encodes a protein that is involved in signal transduction and cytoskeletal organization. Located on chromosome 11, the PLEKHJ1 protein contains a pleckstrin homology (PH) domain, which facilitates its binding to phosphoinositides and the subsequent interaction with cellular membranes. This interaction is vital for various cellular processes, including the regulation of cell shape, motility, and intracellular trafficking. The precise biological functions of PLEKHJ1 are still being elucidated, but its role in these signaling pathways underscores its importance in maintaining cellular architecture and function. Alterations in PLEKHJ1 expression or mutations can have significant implications for cellular dynamics and have been linked to certain pathological conditions, including cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: guanine nucleotide releasing protein x; Guanine nucleotide-releasing protein x; PH domain-containing family J member 1; pleckstrin homology domain containing, family J member 1; Pleckstrin homology domain-containing family J member 1
Gene Aliases: GNRPX; PLEKHJ1
UniProt ID: (Human) Q9NW61
Entrez Gene ID: (Human) 55111
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support