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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63216. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PLC-XD2 (PI-PLC X domain-containing protein 2) is a 305 amino acid protein that contains a domain that is present in many PLC isozymes, the PI-PLC X (X-box)domain. Both the X-box domain and the Y-box domain are important for catalytic activity in PLC proteins. X-box domains are conserved from prokaryotes to mammals. The gene encoding PLC-XD2 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. There are two isoforms of PLC-XD2 that are produced as a result of alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: phosphatidylinositol-specific phospholipase C, X domain containing 2
Entrez Gene ID: (Human) 257068
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