Invitrogen

Human FRY (aa 660-742) Control Fragment Recombinant Protein

Product Details

RP-97919

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

Blocking Assay (BLOCK)

Assay-dependent

Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

EDVLFGFTNFLLREVNDMHHTLLDSSLKLLLQLLTQWKLVIQTQGKVYEQANKIRNSELIANGSSHRIQSERGPHCSVLHAVE

Tag

His-ABP-tag

Class

Recombinant

Type

Protein

Purity

>80% by SDS-PAGE and Coomassie blue staining

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

≥5.0 mg/mL

Purification

purified

Storage buffer

1M urea/PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Product Specific Information

Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).

This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59655. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Target Information

The FRY gene encodes a protein known as furry homolog (FRY), a gene that is highly conserved across species and plays vital roles in cell division and differentiation. FRY is involved in the regulation of mitotic spindle orientation and cellular polarity, crucial for proper cell division and tissue organization. It is found within various tissues and has implications in neurodevelopment and cancer biology, where it influences cell structural properties and signaling pathways. Alterations in FRY expression or mutations can disrupt normal cell function, leading to aberrant cellular morphogenesis and developmental defects. In cancer studies, FRY is associated with tumor suppression, where loss of function contributes to uncontrolled cell proliferation. This gene interacts with other cellular components, such as the cytoskeleton and signaling proteins, orchestrating complex cellular processes essential for maintaining homeostasis and development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: furry homolog; Protein furry homolog; WUGSC:H_2G3A.1

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Gene Aliases: 13CDNA73; 214K23.2; bA207N4.2; bA37E23.1; C13orf14; CG003; FRY