Gibco

Human CCL24 (Eotaxin-2) Recombinant Protein, PeproTech®

Name: Human CCL24 (Eotaxin-2) Recombinant Protein, PeproTech\u00AE
Brand: Gibco
SKU: 300-33-20UG
Availability: InStock

12 References

View all (3) Eotaxin 2 proteins

Datasheet

Tech Support

Datasheet

Tech Support

Testing Data (1)

Human CCL24 (Eotaxin-2) Protein in Functional Assay (Functional)

FIGURE: 1 / 1

Human CCL24 (Eotaxin-2) Protein (300-33-20UG) in Functional

Bioassay analysis of Human CCL24 (Eotaxin-2) Recombinant Protein, PeproTech® (Product # 300-33-1MG).

Product Image Gallery

Product Details

300-33-20UG

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

View 1 publication 1 publication

ELISA (ELISA)

Assay-dependent

View 1 publication 1 publication

Functional Assay (Functional)

Assay-dependent

In vitro Assay (IV)

View 8 publications 8 publications

Miscellaneous PubMed (MISC)

View 2 publications 2 publications

Product Specifications

Species

Human

Published species

Bacteria, Human, Mouse

Expression System

E. coli

Amino acid sequence

VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKGGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA

Molecular weight

8.8 kDa

Class

Recombinant

Type

Protein

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin concentration

<1 EU/µg

Activity

Determined by its ability to chemoattract using human peripheral blood eosinophils using a concentration of 50.0-100.0 ng/ml.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient

Product Specific Information

Recombinant Human Eotaxin-2 is an 8.8 kDa protein containing 78 amino acid residues.

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Target Information

Eotaxin 2 belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.

The Journal of biological chemistry

Lee AW,Deruaz M,Lynch C,Davies G,Singh K,Alenazi Y,Eaton JRO,Kawamura A,Shaw J,Proudfoot AEI,Dias JM,Bhattacharya S

Fri Jul 19 00:00:00 UTC 2019

Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.

Scientific reports

Alenazi Y,Singh K,Davies G,Eaton JRO,Elders P,Kawamura A,Bhattacharya S

Fri Apr 20 00:00:00 UTC 2018

Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.

Scientific reports

Singh K,Davies G,Alenazi Y,Eaton JRO,Kawamura A,Bhattacharya S

Tue Jun 27 00:00:00 UTC 2017

Host chemokines bind to Staphylococcus aureus and stimulate protein A release.

The Journal of biological chemistry

Yung SC,Parenti D,Murphy PM

Fri Feb 18 00:00:00 UTC 2011

Role of the CXCR4/CXCL12 axis in lymphangioleiomyomatosis and angiomyolipoma.

Journal of immunology (Baltimore, Md. : 1950)

Clements D,Markwick LJ,Puri N,Johnson SR

Sun Aug 01 00:00:00 UTC 2010

CCR3 is a target for age-related macular degeneration diagnosis and therapy.

Nature

Takeda A,Baffi JZ,Kleinman ME,Cho WG,Nozaki M,Yamada K,Kaneko H,Albuquerque RJ,Dridi S,Saito K,Raisler BJ,Budd SJ,Geisen P,Munitz A,Ambati BK,Green MG,Ishibashi T,Wright JD,Humbles AA,Gerard CJ,Ogura Y,Pan Y,Smith JR,Grisanti S,Hartnett ME,Rothenberg ME,Ambati J

Thu Jul 09 00:00:00 UTC 2009

The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.

Stem cells (Dayton, Ohio)

Ponte AL,Marais E,Gallay N,Langonné A,Delorme B,Hérault O,Charbord P,Domenech J

Sun Jul 01 00:00:00 UTC 2007

Angiotensin II-induced mononuclear leukocyte interactions with arteriolar and venular endothelium are mediated by the release of different CC chemokines.

Journal of immunology (Baltimore, Md. : 1950)

Mateo T,Abu Nabah YN,Abu Taha M,Mata M,Cerdá-Nicolás M,Proudfoot AE,Stahl RA,Issekutz AC,Cortijo J,Morcillo EJ,Jose PJ,Sanz MJ

Mon May 01 00:00:00 UTC 2006

Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas.

Blood

Trentin L,Cabrelle A,Facco M,Carollo D,Miorin M,Tosoni A,Pizzo P,Binotto G,Nicolardi L,Zambello R,Adami F,Agostini C,Semenzato G

Thu Jul 15 00:00:00 UTC 2004

Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists.

American journal of respiratory and critical care medicine

Bryan SA,Jose PJ,Topping JR,Wilhelm R,Soderberg C,Kertesz D,Barnes PJ,Williams TJ,Hansel TT,Sabroe I

Sat Jun 15 00:00:00 UTC 2002

Differential activation of CC chemokine receptors by AOP-RANTES.

The Journal of biological chemistry

Elsner J,Mack M,Brühl H,Dulkys Y,Kimmig D,Simmons G,Clapham PR,Schlöndorff D,Kapp A,Wells TN,Proudfoot AE

Fri Mar 17 00:00:00 UTC 2000

Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3.

The Journal of biological chemistry

Kitaura M,Suzuki N,Imai T,Takagi S,Suzuki R,Nakajima T,Hirai K,Nomiyama H,Yoshie O

Fri Sep 24 00:00:00 UTC 1999

Bioinformatics

Protein Aliases: C-C motif chemokine 24; chemokine (C-C motif) ligand 24; CK-beta-6; Eosinophil chemotactic protein 2; Eotaxin-2; Eotaxin2; MPIF-2; Myeloid progenitor inhibitory factor 2; small inducible cytokine subfamily A (Cys-Cys), member 24; Small-inducible cytokine A24

Human CCL24 (Eotaxin-2) Recombinant Protein, PeproTech®

Human CCL24 (Eotaxin-2) Protein (300-33-20UG) in Functional

Product Details

300-33-20UG

Western Blot (WB)

ELISA (ELISA)

Functional Assay (Functional)

In vitro Assay (IV)

Miscellaneous PubMed (MISC)

Species

Published species

Expression System

Amino acid sequence

Molecular weight

Class

Type

Purity

Endotoxin concentration

Activity

Conjugate

Form

Purification

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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