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Monkey Osteoactivin/GPNMB quantitates monkey Osteoactivin/GPNMB in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey Osteoactivin/GPNMB.
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : GPNMB, HGFIN, NMB, UNQ1725/PRO9925
Gene ID : (Human) 10457
Gene symbol : GPNMB
Protein Aliases : glycoprotein (transmembrane) nmb, glycoprotein nmb-like protein, glycoprotein nonmetastatic melanoma protein B, hematopoietic growth factor inducible neurokinin-1, Hematopoietic growth factor inducible neurokinin-1 type, osteoactivin, transmembrane glycoprotein HGFIN, Transmembrane glycoprotein NMB
UniProt ID (Human) Q14956
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