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Invitrogen
Human/Rhesus Monkey BLC ELISA Kit
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Product Specifications
Analytical sensitivity
12 pg/mL
Assay range
12-3,000 pg/mL
Sample type/volume
Supernatant
50 µL
Plasma
50 µL
Serum
50 µL
Hands-on time
1 hr 20 min
Time-to-result
4 hr 45 min
Homogenous (no wash)
No
Interassay CV
<12%
Intraassay CV
<10%
Instrument
Absorbance Microplate Reader
Product size
96 Tests
Contents
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Shipping conditions
Wet ice
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Protein name
CXCL13
Species (tested)
Non-human primate
Assay kit format
Sandwich ELISA Kit
Detector antibody conjugate
Biotin
Label or dye
HRP
About This Kit
Monkey BLC quantitates monkey BLC in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey BLC.
Target information
CXCL13, also known as BCA-1 and Angie, is a small chemokine strongly expressed in the secondary lymphoid organs. It preferentially promotes the migration of B lymphocytes (both B-1 and B-2) to the follicles of the spleen, lymph nodes, and Peyer's patches. It is produced by macrophages, and in mouse the highest constitutive producers include large peritoneal macrophages, Kuppfer cells and lung macrophages (both CD11c+ and CD11c-). The cellular ligand for CXCL13 is CXCR5 also known as BLR-1 (Burkitt's Lymphoma Receptor 1). CXCR5 is expressed on B cells, Tfh cells and, to a lower degree, some memory T cell populations. CXCL13 plays an important role in the development of chronic lymphocytic leukemia (CCL). CXCL13 is also a plasma biomarker for germinal center activity and generation of broadly neutralizing antibodies against HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Gene aliases : ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, CXCL13, SCYB13
Gene ID : (Human) 10563
Gene symbol : CXCL13
Protein Aliases : Angie, B cell-attracting chemokine 1, B lymphocyte chemoattractant, B-cell chemoattractant, B-cell-attracting chemokine 1, B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1), B-lymphocyte chemoattractant, BCA-1, C-X-C motif chemokine 13, chem, C Cmotif chemokine, C X C motif chemokine, CC motif chemokine, CCmotif chemokine, CXC, CXC motif chemokine, CXC motif chemokine 13, CXCL, chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant), CXC chemokine BLC, small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant), Small-inducible cytokine B13
UniProt ID (Human) O43927
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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