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Invitrogen
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Immunogen sequence: ALLALEEDIQ ANLIMKRHFT QALSTVTPRI PESLRRFYED YQEKSGLHTL
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Dog: 92%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%
This gene encodes a member of the ATPase associated with diverse activities family, whose members are defined by a highly conserved ATPase domain. Members of this family participate in diverse cellular processes that include membrane fusion, DNA replication, microtubule severing, and protein degradation. The protein encoded by this gene has a putative mitochondrial targeting sequence and has been proposed to function in maintenance of mitochondrial function and integrity during mouse spermatogenesis. Allelic variants in this gene have been associated with epilepsy, hearing loss, and cognitive disability syndrome. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AFG2 AAA ATPase homolog A; ATPase family gene 2 homolog; ATPase family gene 2 protein homolog A; ATPase family protein 2 homolog; Ribosome biogenesis protein SPATA5; spermatogenesis associated factor SPAF; Spermatogenesis-associated factor protein; Spermatogenesis-associated protein 5
Gene Aliases: AFG2; AFG2A; EHLMRS; SPAF; SPATA5
UniProt ID: (Human) Q8NB90
Entrez Gene ID: (Human) 166378
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