Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Reg3D Monoclonal Antibody (518818)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 1
Reg3D Antibody (MA5-24226) in IHC (P)
Immunohistochemical analysis of Reg3D in immersion fixed paraffin-embedded sections of mouse pancreas. Samples were incubated with Reg3D Monoclonal Antibody (Product # MA5-24226) using a dilution of 15 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rat IgG HRP Secondary Antibody. Tissue was stained with DAB (brown) and counterstained with hematoxylin (blue).
Product Details
MA5-24226
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
518818
Immunogen
E. coli-derived recombinant mouse Reg3D Glu27-Gly175
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610620
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human (rh) Reg1A, 1B, recombinant mouse (rm) Reg1, 2, 3A, 3B, 3G, 4, or recombinant rat Reg3 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
The Reg3D gene encodes the regenerating islet-derived protein 3 delta, a member of the Reg protein family, which is involved in tissue regeneration, particularly within the pancreas. Reg3D proteins are known for their significant roles in the protection and regeneration of pancreatic islet cells, aiding in the maintenance of glucose homeostasis during pancreatic stress or damage. They possess bactericidal properties, contributing to the innate immunity of the gastrointestinal tract by providing a defensive mechanism against microbial invasion. The expression of Reg3D is upregulated in response to intestinal bacterial infections, supporting mucosal defenses and preventing pathogen colonization. While closely related to other Reg family members, Reg3D's specific functions and regulatory mechanisms continue to be elucidated, with ongoing research exploring its potential therapeutic applications in conditions such as diabetes and pancreatitis. Understanding the role of Reg3D in pancreatic and gastrointestinal health is crucial for developing strategies to enhance tissue repair and immune functions in related diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: islet neogenesis associated protein-related protein; Reg III delta; regenerating islet-derived 3 delta
Gene Aliases: INGAP; Ingaprp
Entrez Gene ID: (Mouse) 30053
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support