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Invitrogen
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Immunogen sequence: RGSGFIMCSG KENPDSDADL DVDGDDTLEY GKPQYTEADV IPCTGEEPGE AKEREALRGA VLNGGPPSTR ITPEFSKWAS
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin-protein ligase RNF220; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220
Gene Aliases: C1orf164; RNF220
UniProt ID: (Human) Q5VTB9
Entrez Gene ID: (Human) 55182
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