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PA1-24892 detects Orexin A from human, mouse, and rat samples.
PA1-24892 has been successfully used in radioimmune assay procedures.
The PA1-24892 immunogen is a synthetic peptide, conjugated to KLH, corresponding to the N-terminal residues 1-17 of human Orexin A, with a disulfide bridge between cysteines 6-12 and 7-14 and a C-terminal added glycine lysine.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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