Invitrogen

MAS1 Polyclonal Antibody

MAS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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MAS1 Antibody (PA5-77282) in IHC (P)

Immunohistochemistry analysis of MAS1 in paraffin-embedded rat kidney. Samples were probed with MAS1 polyclonal antibody (Product # PA5-77282) using a dilution of 1:100, and incubated with hematoxylin.

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MAS1 Antibody — (C)KIRKNTWASHSSK, corresponding to amino acid residues 212-224 of the rat Angiotensin-(1-7) Mas receptor

Product Details

PA5-77282

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

View 1 publication 1 publication

Immunohistochemistry (IHC)

1:200

View 1 publication 1 publication

Product Specifications

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)KIRKNTWASHSSK, corresponding to amino acid residues 212-224 of the rat Angiotensin-(1-7) Mas receptor

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

AB_2736117

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a 7-transmembrane segment following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogenic effects.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

AVE 0991 Suppresses Astrocyte-Mediated Neuroinflammation of Alzheimer's Disease by Enhancing Autophagy.

Journal of inflammation research

Deng Y,Wang SY,Wang QG,Xu ZH,Peng Q,Chen SY,Zhu L,Zhang YD,Duan R

PA5-77282 was used in Western Blotting to suggest that regulation of autophagy is critical for inhibiting astrocyte neuroinflammatory responses and demonstrate a potential neuroprotective mechanism by which AVE 0991 could suppress neuroinflammatory responses by enhancing autophagy.

Fri Feb 10 00:00:00 UTC 2023

AVE 0991 Suppresses Astrocyte-Mediated Neuroinflammation of Alzheimer's Disease by Enhancing Autophagy.

Journal of inflammation research

Deng Y,Wang SY,Wang QG,Xu ZH,Peng Q,Chen SY,Zhu L,Zhang YD,Duan R

Fri Feb 10 00:00:00 UTC 2023

In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells.

Cells

Saravi B,Li Z,Basoli V,Grad S,Häckel S,Albers CE,Alini M,Schmal H,Obid P,Lang G

PA5-77282 was used in Immunohistochemistry-immunofluorescence to indicate that tRAS modulation might be a novel therapeutic approach to intervertebral disc disease.

Fri Oct 28 00:00:00 UTC 2022

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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