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Invitrogen
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This antibody has specificity for Mouse IGSF5.
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cell adhesion molecule JCAM; IgSF5; Immunoglobulin superfamily member 5; JAM-4; junction adhesion molecule 4; Junctional adhesion molecule 4
Gene Aliases: 2010003D20Rik; Igsf5; Jam4; JCAM
UniProt ID: (Mouse) Q7TSN7
Entrez Gene ID: (Mouse) 72058
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