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Invitrogen
GM-CSF Polyclonal Antibody
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FIGURE: 1 / 2
GM-CSF Antibody (PA1-84972) in IHC (P)
Immunohistochemical staining of formalin-fixed, paraffin-embedded human cervical squamous cell carcinoma using a Granulocyte Macrophage-CSF polyclonal antibody (Product # PA1-84972) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
Product Details
PA1-84972
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant human GM-CSF
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Storage conditions
4°C
Shipping conditions
Wet ice
RRID
AB_2085545
Product Specific Information
Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections.
Reconstitute with 0.1 mL of distilled water. For long term storage 0.09% sodium azide is recommended. After reconstitution, store at -20°C.
This antibody may be used in an indirect ELISA or as a capture reagent in a sandwich ELISA with PA1-84988 as the detection antibody.
Target Information
The GM-CSF gene encodes for a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at the chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13. The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice that lack this gene or its receptor have been shown to develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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