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PA1-20855 detects ERK3 in human, mouse and rat samples.
PA1-20855 has been successfully used in ELISA and Western blot procedures.
The PA1-20855 immunogen is a synthetic peptide to residues H(401) S S S E R F L E Q S H S S M E(416) of human ERK3 protein.
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. Tissue specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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