Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Abnova
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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRGFNLLLFW GCCVMHSWEG HIRPTRKPNT KGNNCRDSTL CPAYATCTNT VDSYYCACKQ GFLSSNGQNH FKDPGVRCKD IDECSQSPQP CGPNSSCKNL SGRYKCSCLD GFSSPTGNDW VPGKPGNFSC TDINECLTSS VCPEHSDCVN SMGSYSCSCQ VGFISRNSTC EDVDECADPR ACPEHATCNN TVGNYSCFCN PGFESSSGHL SFQGLKASCE DIDECTEMCP INSTCTNTPG SYFCTCHPGF APSNGQLNFT DQGVECRDID ECRQDPSTCG PNSICTNALG SYSCGCIAGF HPNPEGSQKD GNFSCQRVLF KCKEDVIPDN KQIQQCQEGT AVKPAYVSFC AQINNIFSVL DKVCENKTTV VSLKNTTESF VPVLKQISTW TKFTKEETSS LATVFLESVE SMTLASFWKP SANITPAVRT EYLDIESKVI NKECSEENVT LDLVAKGDKM KIGCSTIEES ESTETTGVAF VSFVGMESVL NERFFKDHQA PLTTSEIKLK MNSRVVGGIM TGEKKDGFSD PIIYTLENIQ PKQKFERPIC VSWSTDVKGG RWTSFGCVIL EASETYTICS CNQMANLAII MASGELTMGC AIIAGFLHYL FLACFFWMLV EAVILFLMVR NLKVVNYFSS RNIKMLHICA FGYGLPMLVV VISASVQPQG YGMHNRCWLN TETGFIWSFL GPVCTVIVIN SLLLTWTLWI LRQRLSSVNA EVSTLKDTRL LTFKAFAQLF ILGCSWVLGI FQIGPVAGVM AYLFTIINSL QGAFIFLIHC LLNGQVREEY KRWITGKTKP SSQSQTSRIL LSSMPSASKT G
EMR1 has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. EMR1 is the human ortholog of murine F4/80 but unlike F4/80, the expression of EMR1 in humans is restricted to eosinophils and is not expressed on macrophage populations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adhesion G protein-coupled receptor E1; egf-like module containing, mucin-like, hormone receptor-like 1; egf-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor
Gene Aliases: ADGRE1; EMR1; TM7LN3
UniProt ID: (Human) Q14246
Entrez Gene ID: (Human) 2015
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