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Invitrogen
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FIGURE: 1 / 1
Immunogen sequence: NKTWKEMRAT QEDFDKVMQV VREQLARTLA LKPTSLELFR TKVNALTYGE VLRLRQTERL HQEGTLAPPI LELREKLKPE LMGLIRQQRL LRLCEGTLFR KISSRRRQDK LWFCCLSPNH KLLQYGDMEE GASPPTLESL PEQLPVADMR ALLTGKDCPH VREKGSGKQN KDLYELAFSI SYDRGEEEAY LNFIAPSKRE FYLWTDGLSA LLGSPMGSEQ TRLDLEQLLT METKLRLLEL ENVPIPERPP PVPPPPTNFN FCYDCSIAEP; Positive Samples: 22Rv1, SW480, HT-29, Mouse brain, Mouse liver, Mouse kidney, Rat lung; Cellular Location: Cytoplasm
The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ced-12 homolog 3; engulfment and cell motility 3, ced-12 homolog; Engulfment and cell motility protein 3; FLJ13824
Gene Aliases: 9930107J06; BC058752; CED-12; CED12; ELMO-3; ELMO3
UniProt ID: (Human) Q96BJ8, (Rat) Q499U2, (Mouse) Q8BYZ7
Entrez Gene ID: (Human) 79767, (Rat) 291962, (Mouse) 234683
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