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Carboxypeptidase A Polyclonal Antibody, Biotin
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Product Details
NE025-BIO
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carboxypeptidase A from Bovine pancreas
Conjugate
Form
Lyophilized
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Carboxypeptidase A isolated and purified from bovine pancreas. Freund's complete adjuvant is used in the first step of the immunization procedure.
No preservative added, as it may interfere with the antibody activity. No foreign protein added. It is reconstituted by adding 1.0 mL sterile distilled water, spun down to remove insoluble particles, divided into small aliquots, frozen and stored at or below -20°C.
Target Information
CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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