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Invitrogen
COX3 Monoclonal Antibody (DA5BC4)
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FIGURE: 1 / 2
COX3 Antibody (459300) in WB
Western blot analysis of COX3 in isolated heart mitochondria extracts using a COX3 Monoclonal Antibody (Product # 459300) at a concentration of 4 µg/mL. Lane 1 : Isolated mitochondria from Human heart at 5 µg, Lane 2 : Isolated mitochondria Rat heart at 10 µg, Lane 3 : Isolated mitochondria from Mouse heart at 10 µg. Predicted band size: 30 kDa.
Product Details
459300
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat,
Yeast
Published species
Yeast
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
DA5BC4
Immunogen
Full length native Yeast Cytochrome C Oxidase subunit III
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
IgG fraction
Storage buffer
HEPES buffered saline
Contains
0.02% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10374345
Product Specific Information
Positive control: Isolated mitochondria from Human , Rat and Mouse hearts.
WB Predicted molecular weight: 30 kDa.
Target Information
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Co3; Cytochrome c oxidase polypeptide III; Cytochrome c oxidase subunit 3
Gene Aliases: COIII; COX3; COXIII; MT-CO3; MTCO3; OXI2; Q0275
UniProt ID: (Baker's yeast) P00420
Entrez Gene ID: (Mouse) 17710, (Baker's yeast) 854627
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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