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Invitrogen
Bestrophin 2 (extracellular) Polyclonal Antibody
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FIGURE: 1 / 4
Bestrophin 2 (extracellular) Antibody (PA5-77291) in IHC (P)
Immunohistochemistry analysis of Bestrophin 2 (extracellular) in paraffin-embedded rat colon. Samples were probed with Bestrophin 2 (extracellular) polyclonal antibody (Product # PA5-77291) using a dilution of 1:100, and incubated with hematoxylin. Image shows Bestrophin-2 expression in the columnar absorptive cells of the colonic epithelium.
Product Details
PA5-77291
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide (C)DPAQGYKDHTLD, corresponding to amino acid residues 259-270 of mouse Bestrophin-2
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2735520
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt. Reconstitution: add 50 µL of deionized water.
Target Information
Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate. The Best2 gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in the Best2 gene is associated with vitelliform macular dystrophy. The Best2 gene is mainly expressed in the retinal pigment epithelium and colon. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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